Actress and DJ Ruby Rose is no longer a fan of rapper Kanye West, insisting he has crossed too many lines with recent social media remarks and song lyrics about women.

The Orange is the New Black star has tired of Kanye's risque comments about his ex-girlfriend Amber Rose and embattled comedian Bill Cosby, who has been accused of sexually assaulting more than 50 women, but it was the rap star's song lyric about her friend Taylor Swift which served as the final straw.

West debuted songs from his new album T.L.O.P. during a livestreamed New York Fashion Week showcase at Madison Square Garden on Thursday (11Feb16), and he set social media alight with a questionable jab at Taylor, his one-time rival, in the lyrics for Famous.

He rapped, "I feel like me and Taylor might still have sex/Why? I made that b**ch famous."

Swift's best pal Jaime King, who was in the audience, immediately deleted a video from the show she had posted on Instagram out of protest and Swift's brother and model friend Gigi Hadid have criticized Kanye for the reference, which he defended in a recent Twitter spree.

And now Ruby Rose has hit Twitter to declare she has had enough of Kanye.

"Too many lines crossed," the feminist wrote. "If I put myself in the shoes of the women he has hurt recently. Victims of Bill Cosby, The Slut shaming, Amber...

"And now my dear friend Taylor... Right before another huge moment for her... Can I still support him and call myself a feminist? A friend? No."

Taylor is among the stars billed to perform at the Grammy Awards on Monday night (15Feb16).