Outspoken rapper Azealia Banks has taken aim at pop star Zayn Malik once again with transphobic slur.

The 212 star took to Instagram this week (ends12Aug16) to comment on Zayn's new GQ magazine cover and photospread, in which he shows off his tattooed arms in a series of sultry shots.

Commenting on a BallerAlert post featuring a collage of the former One Direction singer's GQ poses, she allegedly wrote, "He legit looks like he used to be a girl. He gives me transman teas (sic)."

The offensive remark prompted Zayn's fans to criticise Azealia for being a cyberbully, three months after she had her Twitter account suspended for directing a foul-mouthed and racist rant at the British star.

Banks lashed out at Zayn in May (16) after he appeared to respond to her comments about the similarities between his Like I Would video, accusing the 23-year-old of copying the concept of her Yung Rapunzel promo.

Her angry outburst featured ill-advised racist jibes about Zayn's Asian roots.