1. Sigourney Weaver
Sigourney Weaver has been a force to be reckoned with since she took down a Xenomorph in 1979’s Alien. Since then, she has widely been considered the First Lady of Sci-Fi and for a good reason. With credits including Aliens, Avatar, and Galaxy Quest, she not only proves she has exceptional range but that she knows how to run the show. Madame Web is one of the most powerful entities within the comics and a matriarch that works from behind the scenes. Sigourney’s charm, wit, and talents would be a stellar choice to play the powerful spider-themed oracle.